Anti-ARFGAP1 antibody
Specifications
| Product Cat#: | AB-06-0363 |
| Product type: | Primary antibody |
| Antigen: | ARFGAP1 |
| Immunogen: | Purified recombinant fragment of human ARFGAP1 expressed in E. Coli. |
| Species immunized: | Mouse |
| Isotype: | IgG2b |
| Applications: | Western Blot (1:400-1:1000); Flow Cytometry (1:40-1:100) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Monoclonal, E2-C4 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | ADP ribosylation factor 1 GTPase activating protein antibody |
| ADP ribosylation factor GTPase activating protein 1 antibody | |
| ADP-ribosylation factor 1 GTPase-activating protein antibody | |
| ADP-ribosylation factor GTPase-activating protein 1 antibody | |
| ARF GAP 1 antibody | |
| ARF1 directed GTPase activating protein antibody | |
| ARF1 GAP antibody | |
| ARF1-directed GTPase-activating protein antibody | |
| ARF1GAP antibody | |
| ARFG1_HUMAN antibody | |
| Arfgap1 antibody | |
| GAP protein antibody | |
| HRIHFB2281 antibody |
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Target information
GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle’s fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine (By similarity).
Provider
Erpantech Laboratory