Anti-Apelin Receptor antibody
Specifications
| Product Cat#: | AB-06-0329 |
| Product type: | Primary antibody |
| Antigen: | Apelin receptor |
| Immunogen: | KLH conjugated synthetic peptide derived from human Apelin receptor 41-140/380 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Flow Cytometry (1μg/test) |
| Reactivity: | Human, Mouse, Rat, Dog, Rabbit |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | APJ receptor |
| AGTR L1 | |
| AGTRL 1 | |
| AGTRL1 | |
| Angiotensin II receptor like 1 | |
| Angiotensin receptor like 1 | |
| Apelin receptor | |
| APJ | |
| B78 | |
| FLJ90771 | |
| G protein coupled receptor APJ | |
| GPCR34 | |
| HG 11 | |
| HG11 | |
| MGC45246 | |
| MSR | |
| Msr/apj | |
| Aplnr | |
| Agtrl1 | |
| APLNR | |
| FLJ96609 |
Target information
Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity (PubMed:11090199, PubMed:25639753, PubMed:28137936). Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone (By similarity). May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis (By similarity). Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development (By similarity). Plays also a role in various processes in adults such as regulation of blood vessel formation, blood pressure, heart contractility and heart failure (PubMed:25639753, PubMed:28137936).
Provider
Erpantech Laboratory
