Anti-APAF1 antibody
Specifications
| Product Cat#: | AB-06-0317 |
| Product type: | Primary antibody |
| Antigen: | APAF1 |
| Immunogen: | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH coupled) corresponding to apoptotic proteaseactivating factor 1. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:1000) |
| Reactivity: | Mouse, Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | APAF 1 antibody |
| Apaf-1 antibody | |
| APAF_HUMAN antibody | |
| Apaf1 antibody | |
| Apoptotic peptidase activating factor 1 antibody | |
| Apoptotic protease activating factor 1 antibody | |
| Apoptotic protease activating factor antibody | |
| Apoptotic protease-activating factor 1 antibody | |
| CED 4 antibody | |
| CED4 antibody | |
| KIAA0413 antibody |
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Target information
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Provider
Erpantech Laboratory
