Anti-Androgen Receptor Recombinant Rabbit Monoclonal antibody
Specifications
| Product Cat#: | AB-06-5054 |
| Product type: | Primary antibody |
| Antigen: | Androgen Receptor |
| Immunogen: | Synthetic peptide within Human Androgen Receptor aa 300-400 (N terminal). |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:1000); Immunohistochemistry-Paraffin (1:200-1000) |
| Reactivity: | Human, Rat |
| Clonality (clone number): | Monoclonal, PO00-29 |
| Form: | Liquid |
| Buffer: | 1*PBS buffer (pH7.4), 0.1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/mL |
| Purity: | Protein A affinity purified. |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Conjugate: | Unconjugated |
| Alternative names: | AIS antibody |
| ANDR_HUMAN antibody | |
| Androgen nuclear receptor variant 2 antibody | |
| Androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) antibody | |
| Androgen receptor antibody | |
| androgen receptor splice variant 4b antibody | |
| AR antibody | |
| AR8 antibody | |
| DHTR antibody | |
| Dihydro testosterone receptor antibody | |
| Dihydrotestosterone receptor (DHTR) antibody | |
| Dihydrotestosterone receptor antibody | |
| HUMARA antibody | |
| HYSP1 antibody | |
| KD antibody | |
| Kennedy disease (KD) antibody | |
| NR3C4 antibody | |
| Nuclear receptor subfamily 3 group C member 4 (NR3C4) antibody | |
| Nuclear receptor subfamily 3 group C member 4 antibody | |
| SBMA antibody | |
| SMAX1 antibody | |
| Spinal and bulbar muscular atrophy (SBMA) antibody | |
| Spinal and bulbar muscular atrophy antibody | |
| Testicular Feminization (TFM) antibody | |
| TFM antibody |
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Target Information
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues (PubMed:19022849).
Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation (PubMed:20812024).
Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3
Provider
Erpantech Laboratory
