Anti-Alpha-1-antitrypsin antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | Alpha-1-antitrypsin |
| Immunogen: | Native protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:200-1:2000); Immunohistochemistry (1:100-1:200); ELISA |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal, 6-D8 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | A1A antibody |
| A1AT antibody | |
| A1AT_HUMAN antibody | |
| AAT antibody | |
| Alpha 1 antiproteinase antibody | |
| Alpha 1 antitrypsin antibody | |
| Alpha 1 antitrypsin null antibody | |
| Alpha 1 protease inhibitor antibody | |
| Alpha-1 protease inhibitor antibody | |
| Alpha-1-antiproteinase antibody | |
| alpha1 proteinase inhibitor antibody | |
| Alpha1AT antibody | |
| Dom1 antibody | |
| PI antibody | |
| PI1 antibody | |
| PRO2275 antibody | |
| Serine (or cysteine) proteinase inhibitor clade A member 1 antibody | |
| Serine protease inhibitor 1-1 antibody | |
| Serine protease inhibitor A1a antibody | |
| Serpin A1 antibody | |
| Serpin A1a antibody | |
| Serpin peptidase inhibitor clade A member 1 antibody | |
| Serpina1 antibody | |
| Short peptide from AAT antibody | |
| SPAAT antibody | |
| Spi1-1 antibody |
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Target information
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.
Short peptide from AAT: reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).
Provider
Erpantech Laboratory
