Anti-ADAMTS4 antibody
Specifications
| Product Cat#: | AB-06-0153 |
| Product type: | Primary antibody |
| Antigen: | ADAMTS4 |
| Immunogen: | KLH conjugated synthetic peptide derived from human ADAMTS4 501-839/839 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000) |
| Reactivity: | Human, Mouse, Rat, Cow, Rabbit, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified. |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | ADAMTS 4 |
| A disintegrin and metalloproteinase with thrombospondin motifs 4 | |
| A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 4 | |
| A disintegrin like and metalloprotease with thrombospondin type 1 motif 4 |
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Target information
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the ‘392-Glu-|-Ala-393’ site.
Provider
Erpantech Laboratory