Anti-ACVL1 antibody
Specifications
| Product Cat#: | AB-07-2289 |
| Product type: | Primary antibody |
| Antigen: | ACVL1 |
| Immunogen: | A synthetic peptide derived from human ACVL1. The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2500); ELISA (1:20000); Immunohistochemistry (1:50-1:100); Immunofluorescence (1:100-1:500) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | ACVL1; ACVRL1; ACVRLK1; ALK-1; Activin receptor-like kinase 1; EC 2.7.11.30; SKR3; TGF-B superfamily receptor type I; TSR-I, kinase ALK1 |
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Target information
Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
Provider
Erpantech Laboratory
