Anti-ACTR-1C antibody
Specifications
| Product Cat#: | AB-07-2286 |
| Product type: | Primary antibody |
| Antigen: | ACTR-1C |
| Immunogen: | A synthetic peptide derived from human ACTR-1C. The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | ELISA (1:20000); Immunohistochemistry (1:50-1:100); Immunofluorescence (1:100-1:500) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Activin receptor type-1C; EC 2.7.11.30; ACTR-IC; Activin receptor-like kinase 7; ALK-7; ACVR1C; ALK7 |
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Target information
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Provider
Erpantech Laboratory
