Anti-Active Caspase-3 antibody
Specifications
| Product Cat#: | AB-06-0134 |
| Product type: | Primary antibody |
| Antigen: | Active Caspase-3 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry (1:100-1:200); Immunocytochemistry (1:100-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal, SR01-02 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Apopain antibody |
| CASP 3 antibody | |
| CASP-3 antibody | |
| CASP3 antibody | |
| CASP3_HUMAN antibody |
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Target information
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a ‘216-Asp-|-Gly-217’ bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Provider
Erpantech Laboratory
