Anti-ABCG2 antibody
Specifications
| Product Cat#: | AB-06-0114 |
| Antibody product type: | Primary antibody |
| Biological source: | Rabbit |
| Application(s): | Western blot (1:1000-2000); Immunocytochemistry (1:100-200); Immunohistochemistry (1:100-200); Flow cytometry (1:50-100) |
| Immunogen: | Recombinant protein |
| Reactivity: | Mouse, Human |
| Isotype: | IgG |
| Clone (Clone number): | Monoclonal |
| Buffer: | 1*Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% Sodium Azide. |
| Form: | Liquid |
| Concentration: | 1 mg/ml |
| Purify: | Protein A affinity purified |
| Storage temp: | Aliquot and freeze at -20C. Avoid multiple freeze/thaw cycles. |
| Other name: | ABC transporter antibody |
| ABC15 antibody | |
| ABCG 2 antibody | |
| ABCG2 antibody | |
| ABCG2_HUMAN antibody |
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target information
High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. Implicated in the efflux of numerous drugs and xenobiotics: mitoxantrone, the photosensitizer pheophorbide, camptothecin, methotrexate, azidothymidine (AZT), and the anthracyclines daunorubicin and doxorubicin.
Provider
Erpantech Laboratory
