Anti-5-HT-1B antibody
Specifications
| Product Cat#: | AB-07-4006 |
| Product type: | Primary antibody |
| Antigen: | 5-HT-1B |
| Immunogen: | The antiserum was produced against synthesized peptide derived from internal of human 5-HT-1B. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2500); Immunofluorescence (1:100-1:500); ELISA (1:5000) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 5-hydroxytryptamine receptor 1B, 5-HT-1B, Serotonin receptor 1B, 5-HT1B, 5-HT-1D-beta, Serotonin 1D beta receptor, S12, HTR1B, HTR1DB |
Target information
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
Provider
Erpantech Laboratory
