Anti-14-3-3 antibody
Specifications
| Product Cat#: | AB-06-0066 |
| Product type: | Primary antibody |
| Antigen: | 14-3-3 protein |
| Immunogen: | Recombinant protein within human 14-3-3 aa 1-100. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry-Paraffin (1:100-1:200) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal, JJ083-6 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 0.05% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 14 3 3 antibody |
| 14 3 3 protein beta antibody | |
| 14 3 3 protein beta/alpha antibody | |
| 14 3 3 protein zeta antibody | |
| 14 3 3 zeta antibody | |
| 14-3-3 protein beta/alpha antibody | |
| 14-3-3 protein/cytosolic phospholipase A2 antibody | |
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| N-terminally processed antibody | |
| Protein 1054 antibody | |
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| YWHAB antibody | |
| YWHAD antibody | |
| YWHAZ antibody |
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TARGET INFORMATION
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13.
PROVIDER
Erpantech Laboratory
