Anti-14-3-3 ε antibody
Specifications
| Product Cat#: | AB-07-3996 |
| Product type: | Primary antibody |
| Antigen: | 14-3-3 ε |
| Immunogen: | The antiserum was produced against synthesized peptide derived from C-terminal of human 14-3-3 ε. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2500); ELISA (1:20000) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 14-3-3E, 143E, KCIP-1, Mitochondrial import stimulation factor L subunit, Protein kinase C inhibitor protein-1, YWHAE |
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Target information
Positively regulates Ras-mediated pathways. Acts downstream or parallel to Raf, but upstream of nuclear factors in Ras signaling. Three mutants have been isolated, that suppress the rough eye phenotype caused by mutated Ras1 (sev-Ras1 v12). Inhibits yki activity by restricting its nuclear localization.
Provider
Erpantech Laboratory
