Anti-BRMS1 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | BRMS1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human BRMS1 151-246/246 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry-Paraffin (1:400-800) |
| Reactivity: | Human, Mouse, Rat, Dog, Pig, Horse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Breast cancer metastasis suppressor 1 |
| Breast cancer metastasis-suppressor 1 | |
| BRMS-1 | |
| BRMS1_HUMAN | |
| DKFZp564A063 | |
| MGC95128 | |
| AV003220 |
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Target information
Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at ‘Lys-310’. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
Provider
Erpantech Laboratory
