Anti-BMPR2 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | BMPR2 |
| Immunogen: | Purified recombinant fragment of human BMPR2 expressed in E. Coli. |
| Species immunized: | Mouse |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:1000); Immunocytochemistry (1:100-1:500); Immunohistochemistry (1:100-1:200) |
| Reactivity: | Mouse, Rat, Human, Monkey |
| Clonality (clone number): | Monoclonal, F8-G6 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | BMP type II receptor antibody |
| BMP type-2 receptor antibody | |
| BMPR 2 antibody | |
| BMPR 3 antibody | |
| BMPR II antibody | |
| BMPR-2 antibody | |
| BMPR-II antibody | |
| Bmpr2 antibody | |
| BMPR2_HUMAN antibody | |
| BMPR3 antibody | |
| BMPRII antibody | |
| BMR 2 antibody | |
| BMR2 antibody | |
| Bone morphogenetic protein receptor type 2 antibody | |
| Bone morphogenetic protein receptor type II antibody | |
| Bone morphogenetic protein receptor type-2 antibody | |
| Bone morphogenic protein receptor type II serine threonine kinase antibody | |
| BRK 3 antibody | |
| BRK3 antibody | |
| PPH 1 antibody | |
| PPH1 antibody | |
| Serine threonine kinase type II activin receptor like kinase antibody | |
| T ALK antibody | |
| TALK antibody | |
| Type II activin receptor like kinase antibody |
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Target information
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
Provider
Erpantech Laboratory