Anti-BMP2 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | BMP2 |
| Immunogen: | Purified recombinant fragment of human BMP2 expressed in E. Coli. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:500-1:2000); Immunocytochemistry (1:100-1:200); Flow Cytometry (1:100-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal, G12-E10 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | BDA2 antibody |
| BMP-2 antibody | |
| BMP-2A antibody | |
| Bmp2 antibody | |
| BMP2_HUMAN antibody | |
| BMP2A antibody | |
| Bone morphogenetic protein 2 antibody | |
| Bone morphogenetic protein 2A antibody |
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Target information
Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451).
Provider
Erpantech Laboratory