Anti-BDH1 antibody
Specifications
| Product Cat#: | AB-06-0488 |
| Product type: | Primary antibody |
| Antigen: | BDH1 |
| Immunogen: | Purified recombinant fragment of human BDH1 expressed in E. Coli |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:500-1:1000); Immunohistochemistry (1:40-1:200) |
| Reactivity: | Mouse, Human |
| Clonality (clone number): | Monoclonal, C3-A5 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 3 hydroxybutyrate dehydrogenase (heart, mitochondrial) antibody |
| 3-hydroxybutyrate dehydrogenase antibody | |
| BDH antibody | |
| BDH_HUMAN antibody | |
| BDH1 antibody | |
| D beta hydroxybutyrate dehydrogenase, mitochondrial antibody | |
| D-beta-hydroxybutyrate dehydrogenase antibody | |
| Mitochondrial antibody |
Target information
BDH1 (3-hydroxybutyrate dehydrogenase, type 1), also known as BDH or SDR9C1, is a 343 amino acid protein that localizes to the mitochondrial matrix and belongs to the short-chain dehydrogenases/reductases (SDR) family. Existing as a homotetramer, BDH1 functions to catalyze the NAD+-dependent interconversion of (R)-3-hydroxybutanoate and acetoacetate, a reaction that is allosterically activated by phosphatidylcholine. As both (R)-3-hydroxybutanoate and acetoacetate are two major ketone bodies produced during fatty acid catabolism, BDH1 plays an important role in the metabolic degradation of fatty acids. The gene encoding BDH1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
Provider
Erpantech Laboratory