Anti-BCL2L10 antibody
Specifications
| Product Cat#: | AB-06-0482 |
| Product type: | Primary antibody |
| Antigen: | BCL2L10 |
| Immunogen: | Purified recombinant fragment of human BCL2L10 expressed in E.Coli. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry (1:100-1:200); Immunocytochemistry (1:100-1:200); Flow Cytometry (1:100-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal, F9-A2 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Anti apoptotic protein NrH antibody |
| Anti-apoptotic protein NrH antibody | |
| Apoptosis regulator Bcl B antibody | |
| Apoptosis regulator Bcl-B antibody | |
| B2L10_HUMAN antibody | |
| BCL B antibody | |
| Bcl-2-like protein 10 antibody | |
| Bcl2 L 10 antibody | |
| BCL2 like 10 (apoptosis facilitator) antibody | |
| BCL2 like 10 protein antibody | |
| Bcl2-L-10 antibody | |
| Bcl2l10 antibody | |
| BCLB antibody | |
| Boo antibody | |
| Diva antibody | |
| MGC129810 antibody | |
| MGC129811 antibody | |
| Nrh antibody |
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Target information
Members of the Bcl-2 family of proteins regulate cell survival by either inhibiting apoptosis or by facilitating the complicated process of cell death. Bcl-B, also known as BCL2L10, Diva, Boo or BCLB, is a widely expressed 194 amino acid member of the Bcl-2 protein family. Localized to the nuclear membrane, Bcl-B promotes cell survival by suppressing BAX-induced apoptosis. Bcl-2 contains a BH4 domain as well as a transmembrane domain, both of which are necessary for its antiapoptotic effects. Overexpression of Bcl-B is thought to prevent the release of cytochrome C from the mitochondria, thereby triggering caspase-3 activation and suppressing cell apoptosis. Bcl-B is implicated in the pathogenesis of cervical cancer.
Provider
Erpantech Laboratory