Human Podocalyxin ELISA kit
Specifications
| Product Cat#: | EK-07-0238 |
| Product name: | Human Podocalyxin ELISA kit |
| Target Name: | PCX |
| Species Reactivity: | Human |
| Product Size: | 48/96 Tests |
| Sensitivity: | 0.04 µg/mL |
| Assay range: | 0.5-10 ng/mL |
| Assay Time: | 90 minutes |
| Platform: | Colorimetric Microplate Reader |
| Conjugate: | HRP |
| ELISA Type: | Competitive ELISA |
| Detection Method: | Colorimetric |
| Storage temperature: | Store at 2-8°C |
| Stability: | Stable within the expiration date under suggested storage conditions |
| Shipping condition: | Wet ice |
| Kit Contents: | Microtiter plate ( 1x ), Enzyme conjugate ( 1 vial ), Standard samples ( 6 vials ), |
| Substrates ( A & B, 2 vials ), Stop solution ( 1 vial ), Wash Solution ( 100x, 1 vial ), | |
| Balance solution ( 1 vial ), Instruction ( 1 copy ) | |
| Other Names of Target: | Podocalyxin; PCLP; PCLP1; Podocalyxin-like Isoform 1 Precursor; Podocalyxin Like Protein; PODXL_HUMAN; GCTM-2 Antigen; Gp200; Podocalyxin-like Protein 1; PC; PCLP-1; PCX; PODXL |
Target information
Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.
Provider
Erpantech Laboratory
