Human Fatty Acid Synthase ELISA kit
Specifications
| Product Cat#: | EK-07-0210 |
| Product name: | Human Fatty Acid Synthase ELISA kit |
| Target Name: | FAS |
| Species Reactivity: | Human |
| Product Size: | 48/96 Tests |
| Sensitivity: | 0.16 ng/mL |
| Assay range: | 2.5-50 ng/mL |
| Assay Time: | 90 minutes |
| Platform: | Colorimetric Microplate Reader |
| Conjugate: | HRP |
| ELISA Type: | Sandwich ELISA |
| Detection Method: | Colorimetric |
| Storage temperature: | Store at 2-8°C |
| Stability: | Stable within the expiration date under suggested storage conditions |
| Shipping condition: | Wet ice |
| Kit Contents: | Microtiter plate ( 1x ), Enzyme conjugate ( 1 vial ), Standard samples ( 6 vials ), |
| Substrates ( A & B, 2 vials ), Stop solution ( 1 vial ), Wash Solution ( 100x, 1 vial ), | |
| Balance solution ( 1 vial ), Instruction ( 1 copy ) | |
| Other Names of Target: | CD95 (phospho Y232); CD95 (phospho Tyr232); p-CD95 (Tyr232); FAS (phospho Y232); FAS (phospho Tyr232); p-FAS (Tyr232); ALPS 1A; ALPS1A; APO 1; Apo 1 Antigen; APO 1 Cell Surface Antigen; Apo-1 Antigen; APO1; Apo1 Antigen; APO1 cell surface antigen; Apoptosis Antigen 1; Apoptosis Mediating Surface Antigen FAS; Apoptosis-mediating Surface Antigen FAS; APT 1; APT1; CD 95; CD 95 Antigen; CD95; CD95 Antigen; Delta Fas; Delta Fas/APO 1/CD95; Delta Fas/APO1/CD95; FAS 1; FAS 827dupA; Fas AMA; FAS; FAS Antigen; FAS1; FASLG Receptor; FASTM; TNF Receptor Superfamily, Member 6; TNFRSF 6; TNFRSF6; TNR6_HUMAN; Tumor Necrosis Factor Receptor Superfamily Member 6 |
Target information
FAS is a receptor for TNFSF6/FASL. The adaptor molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Apoptosis or programmed-cell death is a physiological process essential for the normal development and maintenance of homeostasis in many organisms. This “cellular suicide” can be mediated by the Fas antigen (CD95, APO1), a cell-surface glycoprotein, 40-50kDa, that belongs to the nerve growth factor/tumor necrosis factor (TNF) receptor family. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity). It is type I membrane protein. Contains a death domain involved in the binding of FADD, and maybe to other cytosolic adaptor proteins Contains 1 death domain.
Provider
Erpantech Laboratory
