Human Cyclic Adenosine Monophosphate ELISA Kit
Specifications
| Product Cat#: | EK-07-0162 |
| Product name: | Human Cyclic Adenosine Monophosphate ELISA Kit |
| Target Name: | cAMP |
| Species Reactivity: | Human |
| Product Size: | 48/96 Tests |
| Sensitivity: | 8.8 pmoL/mL |
| Assay range: | 50-1000 pmoL/mL |
| Assay Time: | 90 minutes |
| Platform: | Colorimetric Microplate Reader |
| Conjugate: | HRP |
| ELISA Type: | Competitive ELISA |
| Detection Method: | Colorimetric |
| Storage temperature: | Store at 2-8°C |
| Stability: | Stable within the expiration date under suggested storage conditions |
| Shipping condition: | Wet ice |
| Kit Contents: | Microtiter plate (1x), Enzyme conjugate (1 vial), Standard samples (6 vials), |
| Substrates (A & B, 2 vials), Stop solution (1 vial), Wash Solution (100x, 1 vial), | |
| Balance solution (1 vial), Instruction (1 copy) | |
| Other Names of Target: | cyclic AMP, or 3',5'-cyclic adenosine monophosphate |
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Target information
Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin.
Provider
Erpantech Laboratory
