Rat β Cell Leukemia/Lymphoma 2 ELISA kit
Specifications
| Product Cat#: | EK-07-0445 |
| Product name: | Rat β Cell Leukemia/Lymphoma 2 ELISA kit |
| Target Name: | BCL 2 |
| Species Reactivity: | Rat |
| Product Size: | 48/96 Tests |
| Sensitivity: | 0.25 ng/ml |
| Assay range: | 2.5-50 ng/ml |
| Assay Time: | 90 minutes |
| Platform: | Colorimetric Microplate Reader |
| Conjugate: | HRP |
| ELISA Type: | Competitive ELISA |
| Detection Method: | Colorimetric |
| Storage temperature: | Store at 2-8°C |
| Stability: | Stable within the expiration date under suggested storage conditions |
| Shipping condition: | Wet ice |
| Kit Contents: | Microtiter plate (1x), Enzyme conjugate (1 vial), Standard samples (6 vials), |
| Substrates (A & B, 2 vials), Stop solution (1 vial), Wash Solution (100x, 1 vial), | |
| Balance solution (1 vial), Instruction (1 copy) | |
| Other Names of Target: | B-Cell CLL/lymphoma 2 |
Target information
The Bcl-2 gene was isolated at the chromosomal breakpoint of t-bearing follicular B cell lymphomas.Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal.Bcl-2 appears to function in several subcellular locations yet lacks any known motifs that would confer insight into its mechanism of action .A more recently identified protein,designated Bax p21(i.e., Bcl-associated X protein ),has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activty of Bcl-2.
Provider
Erpantech Laboratory
