Anti-ATG4C antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | ATG4C |
| Immunogen: | Purified recombinant fragment of human ATG4C expressed in E. Coli. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:400-1:2000) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal, H7-E10 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | APG4 autophagy 4 homolog C (S. cerevisiae) antibody |
| APG4 autophagy 4 homolog C antibody | |
| APG4 C antibody | |
| APG4-C antibody | |
| APG4C antibody | |
| ATG 4C antibody | |
| ATG4 autophagy related 4 homolog C (S. cerevisiae) antibody | |
| ATG4 autophagy related 4 homolog C antibody | |
| Atg4c antibody | |
| ATG4C_HUMAN antibody | |
| AUT (S. cerevisiae) like 1, cysteine endopeptidase antibody | |
| AUT like 1, cysteine endopeptidase (S. cerevisiae) antibody | |
| AUT like 1, cysteine endopeptidase antibody | |
| AUT like 3 cysteine endopeptidase antibody | |
| AUT-like 3 cysteine endopeptidase antibody | |
| AUTL1 antibody | |
| AUTL3 antibody | |
| Autophagin 3 antibody | |
| Autophagin-3 antibody | |
| Autophagy related 4C cysteine peptidase antibody | |
| Autophagy related cysteine endopeptidase 3 antibody | |
| Autophagy related protein 4 homolog C antibody | |
| Autophagy-related cysteine endopeptidase 3 antibody | |
| Autophagy-related protein 4 homolog C antibody | |
| Cysteine protease ATG4C antibody | |
| EC 3.4.22 antibody | |
| FLJ14867 antibody | |
| OTTHUMP00000010715 antibody |
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Target information
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Provider
Erpantech Laboratory