Anti-ESRP2 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | ESRP2 |
| Immunogen: | KLH conjugated synthetic peptide derived from human ESRP2 21-120/727 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:200-1:1000); Immunohistochemistry-Paraffin (1:50-200) |
| Reactivity: | Human, Mouse, Rat, Dog, Cow |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Epithelial splicing regulatory protein 2 |
| ESRP 2 | |
| ESRP2 | |
| ESRP2_HUMAN | |
| FLJ21918 | |
| FLJ22248 | |
| RBM35B | |
| RNA binding motif protein 35A | |
| RNA binding motif protein 35B | |
| RNA binding protein 35B | |
| RNA-binding motif protein 35B |
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Target information
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Provider
Erpantech Laboratory
