Anti-NF-κB p65 antibody
Specifications
| Product Cat#: | AB-06-3129 |
| Product type: | Primary antibody |
| Antigen: | NF-κB p65 |
| Immunogen: | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to N-terminal NF-κB p65. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry (1:100-1:200); Flow Cytometry (1:50-1:100) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Peptide affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Avian reticuloendotheliosis viral (v rel) oncogene homolog A antibody |
| MGC131774 antibody | |
| NF kappa B p65delta3 antibody | |
| NFKB3 antibody | |
| Nuclear Factor NF Kappa B p65 Subunit antibody | |
| Nuclear factor NF-kappa-B p65 subunit antibody | |
| Nuclear factor of kappa light polypeptide gene enhancer in B cells 3 antibody | |
| OTTHUMP00000233473 antibody | |
| OTTHUMP00000233474 antibody | |
| OTTHUMP00000233475 antibody | |
| OTTHUMP00000233476 antibody | |
| OTTHUMP00000233900 antibody | |
| p65 antibody |
Target information
NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. In unstimulated cells, NF-κB is sequestered in the cytoplasm by IκB inhibitory proteins. NF-κB-activating agents can induce the phosphorylation of IκB proteins, targeting them for rapid degradation through the ubiquitin-proteasome pathway and releasing NF-κB to enter the nucleus where it regulates gene expression.
Provider
Erpantech Laboratory
