Human Tumor Protein P63 ELISA kit
Specifications
| Product Cat#: | EK-07-0394 |
| Product name: | Human Tumor Protein P63 ELISA kit |
| Target Name: | TP63 |
| Species Reactivity: | Human |
| Product Size: | 48/96 Tests |
| Sensitivity: | 16.9 pg/mL |
| Assay range: | 250-5000 pg/mL |
| Assay Time: | 90 minutes |
| Platform: | Colorimetric Microplate Reader |
| Conjugate: | HRP |
| ELISA Type: | Competitive ELISA |
| Detection Method: | Colorimetric |
| Storage temperature: | Store at 2-8°C |
| Stability: | Stable within the expiration date under suggested storage conditions |
| Shipping condition: | Wet ice |
| Kit Contents: | Microtiter plate (1x), Enzyme conjugate (1 vial), Standard samples (6 vials), |
| Substrates (A & B, 2 vials), Stop solution (1 vial), Wash Solution (100x, 1 vial), | |
| Balance solution (1 vial), Instruction (1 copy) | |
| Other Names of Target: | P63 protein; AIS; Amplified in squamous cell carcinoma; B(p51A); B(p51B); P63 Alpha; Chronic ulcerative stomatitis protein; CUSP; DN p63 alpha 1; DNp63; EEC3; Keratinocyte transcription factor; Keratinocyte transcription factor KET; KET; LMS; NBP; OFC8; P40; P51; P51/P63; P53 like transcription factor; P53 related protein; P53-related protein p63; P53CP; P63; P73; P73H; P73L; RHS; SHFM4; TP53CP; TP53L; P63; TP73; TP73L; Transformation related protein 63; Trp53rp1; Trp63; Tumor protein 63; Tumor protein 63 kDa with strong homology to p53; Tumor protein p53-competing protein; Tumor protein p53-like; Tumor protein p63; Tumor protein p73; Tumor protein p73-like; P63_HUMAN |
Target information
Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.
Provider
Erpantech Laboratory
