Anti-SFRS3 antibody
Specifications
| Product Cat#: | AB-06-4035 |
| Product type: | Primary antibody |
| Antigen: | SFRS3 |
| Immunogen: | Full length recombinant protein. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:600-1:2000); Immunohistochemistry (1:200-1:500); Immunocytochemistry (1:60-1:200) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal (JE46-44) |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | arginine/serine-rich 3 antibody |
| Pre mRNA splicing factor SRP20 antibody | |
| Pre-mRNA-splicing factor SRP20 antibody | |
| Serine/arginine-rich splicing factor 3 antibody | |
| Splicing factor antibody | |
| Splicing factor arginine/serine rich 20 kD antibody | |
| Splicing factor arginine/serine rich 3 antibody | |
| SRp20 antibody | |
| SRSF3 antibody | |
| SRSF3_HUMAN antibody |
Target information
Splicing factor that specifically promotes exon-inclusion during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing . Also functions as export adapter involved in mRNA nuclear export. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. Involved in nuclear export of m6A-containing mRNAs via interaction with YTHDC1: interaction with YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export . RNA-binding is semi-sequence specific .
Provider
Erpantech Laboratory
