Anti-SRY antibody
Specifications
| Product Cat#: | AB-06-4191 |
| Product type: | Primary antibody |
| Antigen: | SRY |
| Immunogen: | Purified recombinant fragment of human SRY expressed in E. Coli. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:600-1:1000); Immunohistochemistry (1:200-1:500); Flow Cytometry (1:80-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (E9-G4) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Purity: | Protein A affinity purified |
| Alternative names: | Essential protein for sex determination in human males antibody |
| Sex determining region on Y antibody | |
| Sex determining region protein antibody | |
| Sex determining region Y antibody | |
| Sex-determining region Y protein antibody | |
| Sox21b antibody | |
| SRXX1 antibody | |
| SRXY1 antibody | |
| SRY 1 antibody | |
| SRY antibody | |
| SRY_HUMAN antibody | |
| Sry1 antibody | |
| Sry3BI antibody | |
| SRYGENE antibody | |
| TDF antibody | |
| TDY antibody | |
| Testis determining factor antibody | |
| Testis Determining Factor on Y antibody | |
| Testis-determining factor antibody | |
| Transcription factor Sox-21-B antibody |
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Target information
Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5′-[AT]AACAA[AT]-3′.
Provider
Erpantech Laboratory
