Anti-WTAP antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | WTAP |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry(1:40-1:200); Immunocytochemistry (1:40-1:200); Flow Cytometry (1:40-1:100) |
| Reactivity: | Human, Monkey |
| Clonality (clone number): | Monoclonal (B6-B6) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DKFZp686F20131 antibody |
| Female-lethal(2)D homolog antibody | |
| FL2D_HUMAN antibody | |
| HFL(2)D antibody | |
| KIAA0105 antibody | |
| MGC3925 antibody | |
| Mum2 antibody | |
| OTTHUMP00000017522 antibody | |
| OTTHUMP00000017523 antibody | |
| PNAS 132 antibody | |
| PNAS-132 antibody | |
| PNAS132 antibody | |
| Pre mRNA splicing regulator WTAP antibody | |
| Pre-mRNA-splicing regulator WTAP antibody | |
| Putative pre mRNA splicing regulator female lethal 2D homolog antibody | |
| Putative pre mRNA splicing regulator female lethal(2D) antibody | |
| Putative pre-mRNA splicing regulator female lethal(2D) homolog antibody | |
| putative pre-mRNA splicing regulator female-lethal(2D) antibody | |
| Wilms tumor 1 associated protein antibody | |
| Wilms tumor 1 associating protein antibody | |
| Wilms tumor 1-associating protein antibody | |
| Wilms' tumor 1 associating protein antibody | |
| Wilms' tumour 1-associating protein antibody | |
| WT1 associated protein antibody | |
| WT1-associated protein antibody | |
| WT1-associating protein antibody | |
| Wtap antibody |
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Target information
Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Required for accumulation of METTL3 and METTL14 to nuclear speckle . Acts as a mRNA splicing regulator.Regulates G2/M cell-cycle transition by binding to the 3′ UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes.
Provider
Erpantech Laboratory
