Anti-XRN2 antibody
Specifications
| Product cat: | AB-06-4673 |
| Product type: | Primary antibody |
| Antigen: | XRN2 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:900-1:2400); Immunohistochemistry (1:90-1:260) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 5' 3' exoribonuclease 2 antibody |
| DHM1 like protein antibody | |
| DHP protein antibody | |
| XRN 2 antibody |
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Target information
Possesses 5′->3′ exoribonuclease activity (By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5′ fragment which is subsequently processed to form the mature mRNA and a 3′ fragment which remains attached to the elongating polymerase. The processive degradation of this 3′ fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites (PubMed:21700224).
Provider
Erpantech Laboratory
