Anti-EIF2C3/ Argonaute 3 antibody
Specifications
| Product Cat#: | AB-06-1525 |
| Product type: | Primary antibody |
| Antigen: | EIF2C3/ Argonaute 3 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:1000); Immunohistochemistry (1:80-1:200); Immunocytochemistry (1:80-1:500); Flow Cytometry (1:40-1:100); Immunofluorescence |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal (JJ201-07) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 5730550L01Rik Antibody |
| Ago 3 Antibody | |
| Ago3 Antibody | |
| AGO3_HUMAN Antibody | |
| argonaute 3 Antibody | |
| Argonaute3 Antibody | |
| eIF 2C 3 Antibody | |
| eIF-2C 3 Antibody | |
| eIF2C 3 antibody | |
| Eif2c3 Antibody | |
| EIF2C3 Protein Antibody | |
| Eukaryotic Translation Initiation Factor 2C 3 Antibody | |
| Eukaryotic Translation Initiation Factor 2C3 Antibody | |
| FLJ12765 Antibody | |
| hAgo3 Antibody | |
| MGC86946 Antibody | |
| Protein Argonaute-3 Antibody |
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Target information
Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5′- and 3′-flanking sequences to the region of guide-target complementarity.
Provider
Erpantech Laboratory
