Anti-SOCS2 antibody
Specifications
| Product cat: | AB-06-4142 |
| Product type: | Primary antibody |
| Antigen: | SOCS2 |
| Immunogen: | Recombinant protein within human SOCS2 1-150aa. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:900-1:2400); Immunocytochemistry (1:100-1:250); Immunofluorescence; Immunoprecipitation |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JG36-86) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CIS 2 antibody |
| CIS-2 antibody | |
| CIS2 antibody | |
| Cish 2 antibody | |
| Cish2 antibody | |
| Cytokine SH2 protein 2 antibody | |
| Cytokine-inducible SH2 protein 2 antibody | |
| SOCS 2 antibody | |
| SOCS-2 antibody | |
| Socs2 antibody | |
| SOCS2_HUMAN antibody | |
| SSI 2 antibody | |
| SSI-2 antibody | |
| SSI2 antibody | |
| STAT induced STAT inhibitor 2 antibody | |
| STAT-induced STAT inhibitor 2 antibody | |
| STATI 2 antibody | |
| STATI2 antibody | |
| Suppressor of cytokine signaling 2 antibody |
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Target information
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Provider
Erpantech Laboratory