Anti-EEF2 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | EEF2 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:400-1:1000); Immunohistochemistry (1:80-1:200); Immunocytochemistry (1:80-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (H1-B6) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | EEF 2 antibody |
| Eef2 antibody | |
| EF-2 antibody | |
| EF2 antibody | |
| EF2_HUMAN antibody | |
| Elongation factor 2 antibody | |
| Eukaryotic translation elongation factor 2 antibody | |
| Polypeptidyl tRNA translocase antibody | |
| SCA26 antibody |
Target information
Two elongation factors (EF) EF-Tu and EF-2 participate in the elongation phase during protein biosynthesis on the ribosome and their functional cycles depend on GTP binding and its hydrolysis. EF-Tu (also designated mitochondrial precursor p43) and EF-2 are multidomain GTPases with essential functions in translation, and they both bind to the same site on the ribosome where their low intrinsic GTPase activities are strongly stimulated. EF-Tu plays a central role in the fast and accurate delivery of aminoacyl-tRNAs to the translating ribosome. In addition, EF-Tu protects the aminoester bond against hydrolysis until a correct match between the codon on mRNA and the anticodon on tRNA can be achieved. EF-2 supports the translocation of tRNAs and of mRNAs on the ribosome so that a new codon can be exposed for decoding.
Provider
Erpantech Laboratory
