Anti-E-Cadherin antibody
Specifications
| Product Cat#: | AB-06-1492 |
| Product type: | Primary antibody |
| Antigen: | E-Cadherin |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot ( 1:800-1:1000 ); Immunohistochemistry ( 1:100-1:200 ); Immunocytochemistry ( 1:100-1:200 ); Flow Cytometry ( 1:50-1:150 ) |
| Reactivity: | Mouse and Human |
| Clonality (clone number): | Monoclonal ( A0-G11-2 ) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer ( pH7.4 ), 1 % BSA, 40 % glycerol, 0.05 % NaN3. |
| Concentration: | 2 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Arc 1 Antibody |
| CADH1_HUMAN Antibody | |
| Cadherin 1 Antibody | |
| cadherin 1 Type 1 E-cadherin Antibody | |
| Cadherin1 Antibody | |
| CAM 120/80 Antibody | |
| CD 324 Antibody | |
| CD324 Antigen Antibody | |
| cdh1 Antibody | |
| CDHE Antibody | |
| E-Cad/CTF3Antibody | |
| E-cadherin Antibody | |
| ECAD Antibody | |
| Epithelial Cadherin Antibody | |
| epithelial Calcium Dependant Adhesion Protein Antibody | |
| LCAM Antibody | |
| Liver Cell Adhesion Molecule Antibody | |
| UVO Antibody | |
| Uvomorulin Antibody |
Target information
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 (By similarity).E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production (By similarity).(Microbial infection) Does not function as a receptor for L.monocytogenes internalin A (InlA); mutating a single surface-exposed residue confers receptor activity to this protein and promotes uptake of the bacteria.
Provider
Erpantech Laboratory
