Anti-Smad2 antibody
Specifications
| Product Cat#: | |
| Product type: | Primary antibody |
| Antigen: | Smad2 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:300-1:1000); Immunoprecipitation; Immunohistochemistry (1:30-1:200); Flow Cytometry (1:30-1:100); Immunocytochemistry (1:30-1:200)) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal (SP06-05) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Drosophila, homolog of, MADR2 antibody |
| hMAD-2 Antibody | |
| HsMAD2 Antibody | |
| JV18 Antibody | |
| JV18-1 Antibody | |
| JV181 Antibody | |
| MAD Antibody | |
| MAD Homolog 2 Antibody | |
| MAD Related Protein 2 Antibody | |
| Mad-related Protein 2 Antibody | |
| MADH2 Antibody | |
| MADR2 Antibody | |
| MGC22139 Antibody | |
| MGC34440 antibody | |
| Mother Against DPP Homolog 2 Antibody | |
| Mothers Against Decapentaplegic Homolog 2 Antibody | |
| Mothers Against Decapentaplegic, Drosophila, Homolog of, 2 Antibody | |
| Mothers against DPP homolog 2 Antibody | |
| OTTHUMP00000163489 Antibody | |
| Sma and Mad Related Protein 2 Antibody | |
| Sma- and Mad-related Protein 2 MAD Antibody | |
| SMAD 2 Antibody | |
| SMAD Family Member 2 Antibody | |
| SMAD, Mothers Against DPP Homolog 2 Antibody | |
| SMAD2 Antibody | |
| SMAD2_HUMAN Antibody |
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Target information
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Provider
Erpantech Laboratory