Anti-Smad2 antibody
Specifications
| Product Cat#: | AB-06-4111 |
| Product type: | Primary antibody |
| Antigen: | Smad2 |
| Immunogen: | Rabbit Polyclonal Antibody |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Immunohistochemistry ( 1:80-1:200 ); Immunocytochemistry ( 1:80-1:100 ) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer ( pH7.4 ), 1 % BSA, 40 % glycerol, 0.05 % NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Peptide affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Drosophila, Homolog of, MADR2 Antibody |
| hMAD-2 Antibody | |
| HsMAD2 Antibody | |
| JV18 Antibody | |
| JV18-1 Antibody | |
| JV181 Antibody | |
| MAD Antibody | |
| MAD Homolog 2 Antibody | |
| MAD Related Protein 2 Antibody | |
| Mad-related Protein 2 Antibody | |
| MADH2 Antibody | |
| MADR2 Antibody | |
| MGC22139 Antibody | |
| MGC34440 Antibody | |
| Mother Against DPP Homolog 2 Antibody | |
| Mothers Against Decapentaplegic Homolog 2 Antibody | |
| Mothers Against Decapentaplegic, Drosophila, Homolog of, 2 Antibody | |
| Mothers Against DPP Homolog 2 Antibody | |
| OTTHUMP00000163489 Antibody | |
| Sma and Mad Related Protein 2 Antibody | |
| Sma- and Mad-related Protein 2 MAD Antibody | |
| SMAD 2 Antibody | |
| SMAD Family Member 2 Antibody | |
| SMAD, Mothers Against DPP homolog 2 Antibody | |
| SMAD2 Antibody | |
| SMAD2_HUMAN Antibody |
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Target information
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Provider
Erpantech Laboratory
