Anti-PTPN12 antibody
Specifications
| Product Cat#: | AB-06-3760 |
| Product type: | Primary antibody |
| Antigen: | PTPN12 |
| Immunogen: | KLH conjugated synthetic peptide derived from human PTPN12 1-100/780 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:600-1:2000) |
| Reactivity: | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Protein tyrosine phosphatase G1 |
| Protein tyrosine phosphatase non receptor type 12 | |
| Protein-tyrosine phosphatase G1 | |
| PTN12_HUMAN | |
| PTP PEST | |
| PTP-PEST | |
| PTPG1 | |
| Ptpn12 | |
| Tyrosine protein phosphatase non receptor type 12 |
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Target information
Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades (PubMed:18559503). Dephosphorylates cellular tyrosine kinases, such as ERBB2 and PTK2B/PYK2, and thereby regulates signaling via ERBB2 and PTK2B/PYK2 (PubMed:17329398, PubMed:27134172). Selectively dephosphorylates ERBB2 phosphorylated at ‘Tyr-1112’, ‘Tyr-1196’, and/or ‘Tyr-1248’ (PubMed:27134172).
Provider
Erpantech Laboratory
