Anti-CBX7 antibody
Specifications
| Product Cat#: | AB-06-0795 |
| Product type: | Primary antibody |
| Antigen: | CBX7 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:550-1:2000); Flow Cytometry (1:60-1:100) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JM44-63) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Cbx 7 antibody |
| CBX7 antibody | |
| Chromobox homolog 7 antibody | |
| Chromobox protein homolog 7 antibody |
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Target information
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ‘Lys-119’, rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at ‘Lys-9’ (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
Provider
Erpantech Laboratory
