Anti-c-Fos antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | c-Fos |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:900); Flow Cytometry (1:40-1:100) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JJ0938) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Activator protein 1 antibody |
| AP 1 antibody | |
| C FOS antibody | |
| Cellular oncogene c fos antibody | |
| Cellular oncogene fos antibody | |
| FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS) antibody | |
| FBJ murine osteosarcoma viral oncogene homolog antibody | |
| FBJ murine osteosarcoma viral v fos oncogene homolog antibody | |
| FBJ Osteosarcoma Virus antibody | |
| FOS antibody | |
| FOS protein antibody | |
| FOS_HUMAN antibody | |
| G0 G1 switch regulatory protein 7 antibody | |
| G0/G1 switch regulatory protein 7 antibody | |
| G0S7 antibody | |
| Oncogene FOS antibody | |
| P55 antibody | |
| Proto oncogene c Fos antibody | |
| Proto oncogene protein c fos antibody | |
| Proto-oncogene c-Fos antibody |
Target information
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.
Provider
Erpantech Laboratory