Anti-PIK3CG antibody
Specifications
| Product Cat#: | AB-06-3583 |
| Product type: | Primary antibody |
| Antigen: | PIK3CG |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (D2-B5) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 1 Phosphatidylinositol 3 Kinase antibody |
| 5-bisphosphate 3-Kinase 110 kDa Catalytic Subunit Gamma antibody | |
| 5-bisphosphate 3-Kinase Catalytic Subunit Gamma isoform antibody | |
| p110 Gamma antibody | |
| p120 PI3K antibody | |
| p120-PI3K antibody | |
| Phosphatidylinositol 3 Kinase Catalytic 110 kD Gamma antibody | |
| Phosphatidylinositol 3 Kinase Gamma, p110 Gamma antibody | |
| Phosphatidylinositol 3 Kinase, Catalytic, Gamma Polypeptide antibody | |
| Phosphatidylinositol 4 5 Bisphosphate 3 Kinase 110 kDa catalytic subunit Gamma antibody | |
| Phosphatidylinositol 4 5 Bisphosphate 3 Kinase Catalytic Subunit Gamma antibody | |
| Phosphatidylinositol 4 5 Bisphosphate 3 Kinase Catalytic Subunit Gamma Isoform antibody | |
| Phosphatidylinositol-4 antibody | |
| Phosphoinositide 3 Kinase Catalytic Gamma Polypeptide antibody | |
| Phosphoinositide 3 Kinase Gamma Catalytic Subunit antibody | |
| PI3 Kinase p110 Subunit Gamma antibody | |
| PI3-Kinase Subunit Gamma antibody | |
| PI3CG antibody | |
| PI3K antibody | |
| PI3K-Gamma antibody | |
| PI3K Gamma antibody | |
| PIK3 antibody | |
| Pik3cg antibody | |
| PK3CG_HUMAN antibody |
Target information
Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Links G-protein coupled receptor activation to PIP3 production. Involved in immune, inflammatory and allergic responses. Modulates leukocyte chemotaxis to inflammatory sites and in response to chemoattractant agents. May control leukocyte polarization and migration by regulating the spatial accumulation of PIP3 and by regulating the organization of F-actin formation and integrin-based adhesion at the leading edge. Controls motility of dendritic cells. Together with PIK3CD is involved in natural killer (NK) cell development and migration towards the sites of inflammation. Participates in T-lymphocyte migration. Regulates T-lymphocyte proliferation and cytokine production. Together with PIK3CD participates in T-lymphocyte development.
Provider
Erpantech Laboratory