Anti-PTBP1 antibody
Specifications
| Product Cat#: | AB-06-3743 |
| Product type: | Primary antibody |
| Antigen: | PTBP1 |
| Immunogen: | Peptide |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:600-1:2000); Immunohistochemistry (1:60-1:200) |
| Reactivity: | Rat, Human |
| Clonality (clone number): | Monoclonal (5C1) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 2 mg/ml |
| Purity: | Peptide affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 57 kDa RNA binding protein PPTB 1 antibody |
| 57 kDa RNA-binding protein PPTB-1 antibody | |
| Heterogeneous nuclear ribonucleoprotein I antibody | |
| Heterogeneous Nuclear Ribonucleoprotein Polypeptide I antibody | |
| hnRNP I antibody | |
| HNRNP-I antibody | |
| HNRNPI antibody | |
| HNRPI antibody | |
| MGC10830 antibody | |
| MGC8461 antibody | |
| Polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) antibody | |
| Polypyrimidine Tract Binding Protein 1 antibody | |
| Polypyrimidine tract binding protein antibody | |
| pPTB antibody | |
| PTB 1 antibody | |
| PTB 2 antibody | |
| PTB 3 antibody | |
| PTB 4 antibody | |
| PTB antibody | |
| PTB T antibody | |
| PTB1 antibody | |
| PTB2 antibody | |
| PTB3 antibody | |
| PTB4 antibody | |
| PTBP 1 antibody | |
| PTBP1 antibody | |
| PTBT antibody |
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Target information
Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806).
Provider
Erpantech Laboratory