Anti-Phosphotyrosine antibody
Specifications
| Product Cat#: | AB-06-3567 |
| Product type: | Primary antibody |
| Antigen: | Phosphotyrosine |
| Immunogen: | Synthetic peptide conjugated to Keyhole Limpet Haemocyanin (KLH) |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:1000); Immunoprecipitation; Immunofluorescence; Immunocytochemistry (1:50); Flow Cytometry (1:10-1:50) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JA10-49) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
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Target information
Tyrosine phosphorylation plays a key role in cellular signaling. Research studies have shown that in cancer, unregulated tyrosine kinase activity can drive malignancy and tumor formation by generating inappropriate proliferation and survival signals. Antibodies specific for phospho-tyrosine have been invaluable reagents in these studies. The phospho-tyrosine monoclonal antibodies developed by Cell Signaling Technology are exceptionally sensitive tools for studying tyrosine phosphorylation and monitoring tyrosine kinase activity in high throughput drug discovery.
Provider
Erpantech Laboratory