Anti-Phospho-SHP2 (Y542) antibody
Specifications
| Product Cat#: | AB-06-3550 |
| Product type: | Primary antibody |
| Antigen: | Phospho-SHP2 (Y542) |
| Immunogen: | Synthetic phospho-peptide corresponding to residues surrounding Tyr542 of human SHP2 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:1000); Immunoprecipitation; Immunocytochemistry (1:50-1:200) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Monoclonal (SN61-01) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | BPTP3 antibody |
| CFC antibody | |
| JMML antibody | |
| METCDS antibody | |
| MGC14433 antibody | |
| NS1 antibody | |
| OTTHUMP00000166107 antibody | |
| OTTHUMP00000166108 antibody | |
| Protein tyrosine phosphatase 2 antibody | |
| Protein tyrosine phosphatase 2C antibody | |
| Protein tyrosine phosphatase non receptor type 11 antibody | |
| Protein-tyrosine phosphatase 1D antibody | |
| Protein-tyrosine phosphatase 2C antibody | |
| PTN11_HUMAN antibody | |
| PTP-1D antibody | |
| PTP-2C antibody | |
| PTP1D antibody | |
| PTP2C antibody | |
| PTPN11 antibody | |
| SAP2 antibody | |
| SH-PTP2 antibody | |
| SH-PTP3 antibody | |
| SH2 domain containing protein tyrosine phosphatase 2 antibody | |
| SHP 2 antibody | |
| SHP-2 antibody | |
| Shp2 antibody | |
| SHPTP2 antibody | |
| SHPTP3 antibody | |
| Syp antibody | |
| Tyrosine-protein phosphatase non-receptor type 11 antibody |
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Target information
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway (PubMed:28074573). Dephosphorylates GAB1, ARHGAP35 and EGFR (PubMed:28074573). Dephosphorylates ROCK2 at ‘Tyr-722’ resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73 (PubMed:26742426).
Provider
Erpantech Laboratory
