Anti-Proteasome 20S C2 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | Proteasome 20S C2 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Immunoprecipitation; Western Blot (1:600-1:2000); Immunohistochemistry (1:60-1:200); Flow Cytometry (1:60-1:100) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal (JB89-30) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4),1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 30 kDa prosomal protein antibody |
| HC 2 antibody | |
| HC2 antibody | |
| Macropain subunit C2 antibody | |
| Macropain subunit nu antibody | |
| MGC14542 antibody | |
| MGC14575 antibody | |
| MGC14751 antibody | |
| MGC1667 antibody | |
| MGC21459 antibody | |
| MGC22853 antibody | |
| MGC23915 antibody | |
| Multicatalytic endopeptidase complex subunit C2 antibody | |
| NU antibody | |
| PROS 30 antibody | |
| PROS-30 antibody | |
| PROS30 antibody | |
| Proteasome (prosome macropain) subunit alpha type 1 antibody | |
| Proteasome alpha 1 subunit antibody | |
| Proteasome component C2 antibody | |
| Proteasome nu chain antibody | |
| Proteasome subunit alpha type 1 antibody | |
| Proteasome subunit alpha type I antibody | |
| Proteasome subunit alpha type-1 antibody | |
| Proteasome subunit nu antibody | |
| Protein P30 33K antibody | |
| PSA1_HUMAN antibody | |
| PSC 2 antibody | |
| PSC2 antibody | |
| PSMA 1 antibody | |
| psmA1 antibody |
Target information
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
Provider
Erpantech Laboratory
