Anti-pro Caspase 3 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | pro Caspase 3 |
| Immunogen: | Recombinant protein |
| Molecular weight: | Predicted band size: 32 kDa, Observed band size: 32 kDa |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry (1:60-1:200); Immunocytochemistry/Immunofluorescence (1:80-1:500); Flow Cytometry (1:60-1:100); Immunoprecipitation |
| Reactivity: | Mouse, Human |
| Clonality (clone number): | Monoclonal (SZ02-08) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 0.05% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CASP3 antibody |
| Caspase 3 antibody | |
| Caspase 3 apoptosis related cysteine peptidase antibody | |
| CPP32 antibody | |
| CPP32B antibody | |
| Procaspase 3 antibody | |
| SCA 1 antibody | |
| SCA1 antibody | |
| Yama antibody | |
| Yama protein antibody |
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Target information
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a ‘216-Asp-|-Gly-217’ bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Provider
Erpantech Laboratory