Anti-CDC42 antibody
Specifications
| Product Cat#: | AB-06-0986 |
| Product type: | Primary antibody |
| Antigen: | CDC42 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:900); Immunohistochemistry (1:40-1:200); Flow Cytometry (1:40-1:100); Immunoprecipitation |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JJ086-04) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CDC42 antibody |
| CDC42_HUMAN antibody | |
| CDC42Hs antibody | |
| Cell division control protein 42 homolog antibody | |
| Cell division cycle 42 (GTP binding protein 25kDa) antibody | |
| Cell division cycle 42 antibody | |
| DJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)) antibody | |
| DJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)) antibody | |
| G25K antibody | |
| G25K GTP-binding protein antibody | |
| Growth regulating protein antibody | |
| GTP binding protein 25kDa antibody | |
| Small GTP binding protein CDC42 antibody | |
| TKS antibody |
Target information
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase . Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections. Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons. Facilitates filopodia formation upon DOCK11-activation (By similarity). Upon activation by CaMKII, modulates dendritic spine structural plasticity by relaying CaMKII transient activation to synapse-specific, long-term signaling (By similarity). Also plays a role in phagocytosis through organization of the F-actin cytoskeleton associated with forming phagocytic cups.
Provider
Erpantech Laboratory
