Anti-USP9x antibody
Specifications
| Product Cat#: | AB-06-4563 |
| Product type: | Primary antibody |
| Antigen: | USP9x |
| Immunogen: | Recombinant protein within human USP9X aa 1-200. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry (1:40-1:200); Flow Cytometry (1:40-1:100); Immunocytochemistry (1:40-1:200); Immunofluorescence |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JG35-11) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Deubiquitinating enzyme FAF X antibody |
| Deubiquitinating enzyme FAF-X antibody | |
| DFFRX antibody | |
| Drosophila fat facets related X linked antibody | |
| FAF antibody | |
| Fafl antibody | |
| Fam antibody | |
| Fat facets homolog antibody | |
| Fat facets in mammals antibody | |
| Fat facets protein related X linked antibody | |
| Fat facets protein related, X-linked antibody | |
| Fat facets protein-related antibody | |
| HFAM antibody | |
| MRX99 antibody | |
| Probable ubiquitin carboxyl terminal hydrolase FAF X antibody | |
| Probable ubiquitin carboxyl-terminal hydrolase FAF-X antibody | |
| Ubiquitin carboxyl-terminal hydrolase FAM antibody | |
| Ubiquitin specific peptidase 9 X linked antibody | |
| Ubiquitin specific peptidase 9, X-linked antibody | |
| Ubiquitin specific processing protease FAF X antibody | |
| Ubiquitin specific protease 9 X chromosome antibody | |
| Ubiquitin thioesterase FAF X antibody | |
| Ubiquitin thiolesterase FAF X antibody | |
| Ubiquitin thiolesterase FAF-X antibody | |
| Ubiquitin-specific protease 9 antibody | |
| Ubiquitin-specific-processing protease FAF-X antibody | |
| USP9 (gene name) antibody | |
| Usp9x antibody | |
| USP9X_HUMAN antibody | |
| Uubiquitin specific protease 9, X chromosome (fat facets like Drosophila) antibody | |
| X chromosome antibody |
Target information
Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Specifically hydrolyzes ‘Lys-48’-, ‘Lys-29’- and ‘Lys-33’-linked polyubiquitins chains. Essential component of TGF-beta/BMP signaling cascade. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Deubiquitinates alkylation repair enzyme ALKBH3. OTUD4 recruits USP7 and USP9X to stabilize ALKBH3, thereby promoting the repair of alkylated DNA lesions . Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Involved in axonal growth and neuronal cell migration. Regulates cellular clock function by enhancing the protein stability and transcriptional activity of the core circadian protein ARNTL/BMAL1 via its deubiquitinating activity.
Provider
Erpantech Laboratory
