Anti-Usp14 antibody
Specifications
| Product Cat#: | AB-06-4556 |
| Product type: | Primary antibody |
| Antigen: | Usp14 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry (1:40-1:200); Flow Cytometry (1:40-1:100); Immunocytochemistry (1:40-1:200); Immunofluorescence |
| Reactivity: | Human, Zebrafish |
| Clonality (clone number): | Monoclonal (JU30-49) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Deubiquitinating enzyme 14 antibody |
| TGT antibody | |
| TRNA guanine transglycosylase 60 kD subunit antibody | |
| TRNA guanine transglycosylase antibody | |
| Ubiquitin carboxyl terminal hydrolase 14 antibody | |
| Ubiquitin carboxyl-terminal hydrolase 14 antibody | |
| Ubiquitin specific peptidase 14 antibody | |
| Ubiquitin specific processing protease 14 antibody | |
| Ubiquitin specific protease 14 antibody | |
| Ubiquitin thiolesterase 14 antibody | |
| Ubiquitin-specific-processing protease 14 antibody | |
| UBP14_HUMAN antibody | |
| USP 14 antibody | |
| USP14 antibody |
Target information
Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs). Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation.
Provider
Erpantech Laboratory
