Anti-CD18 antibody
Specifications
| Product Cat#: | AB-06-0867 |
| Product type: | Primary antibody |
| Antigen: | CD18 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot ( 1:300-1:1000 ); Immunoprecipitation ( 1:20-1:50 ) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal(JM71-31) |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 95 Subunit Beta Antibody |
| Beta 2 (antigen CD18 (p95) Antibody | |
| CD 18 Antibody | |
| CD18 Antibody | |
| Cell Surface Adhesion Glycoprotein LFA 1/CR3/P150,959 Beta Subunit precursor) Antibody | |
| Cell Surface Adhesion Glycoproteins LFA 1/CR3/p150,95 Subunit Beta Antibody | |
| Cell Surface Adhesion Glycoproteins LFA-1/CR3/p150 Antibody | |
| Complement Component 3 Receptor 3 and 4 Subunit Antibody | |
| Complement Receptor C3 Beta Subunit Antibody | |
| Complement Receptor C3 Subunit Beta Antibody | |
| Integrin Beta 2 Antibody | |
| Integrin Beta Chain beta 2 Antibody | |
| Integrin Beta-2 (ITGB2) Antibody | |
| Integrin Beta-2 Antibody | |
| Integrin, Beta 2 (Complement Component 3 Receptor 3 and 4 Subunit) Antibody | |
| ITB2_HUMAN Antibody | |
| ITGB2 Antibody | |
| LAD Antibody | |
| LCAMB Antibody | |
| Leukocyte Associated Antigens CD18/11A, CD18/11B, CD18/11C Antibody | |
| Leukocyte Cell Adhesion Molecule CD18 antibody | |
| LFA 1 Antibody | |
| LFA1 Antibody | |
| Lymphocyte Function Associated Antigen 1 (LFA1) Antibody | |
| Lymphocyte Function Associated Antigen 1 Antibody | |
| MAC 1 Antibody | |
| MAC1 Antibody | |
| Macrophage Antigen 1 (mac1) Beta Antibody | |
| MF17 Antibody | |
| MFI7 Antibody | |
| OTTHUMP00000115278 Antibody | |
| OTTHUMP00000115279 Antibody | |
| OTTHUMP00000115280 Antib |
Target information
Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL . Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. Integrin ITGAL/ITGB2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages. In association with alpha subunit ITGAM/CD11b, required for CD177-PRTN3-mediated activation of TNF primed neutrophils.
Provider
Erpantech Laboratory
