Anti-CYP8B1 antibody
Specifications
| Product Cat#: | AB-06-1255 |
| Product type: | Primary antibody |
| Antigen: | CYP8B1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human CYP8B1 151-250/501 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry-Paraffin (1:400-1:800) |
| Reactivity: | Human, Mouse, Cow, Horse, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10mM Tris-HCl buffer (pH7.4), 1% BSA, 50% glycerol, 0.03% Proclin300. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase |
| 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase | |
| CP8B1_HUMAN | |
| CYP12 | |
| CYP8B1 | |
| CYPVIIIB1 | |
| Cytochrome P450 8B1 | |
| Cytochrome P450, family 8, subfamily B, polypeptide 1 |
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Target information
Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.
Provider
Erpantech Laboratory